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Journal | Year | Drug | Authors | Title | Source |
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Am J Emerg Med | 1998 | Risperidone | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Benzodiazepines | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | SSRI | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Ethanol | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Tricyclics | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Lithium | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Anticonvulsants | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Diphenhydramine | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Ibuprofen | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Anticholinergics | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Antiarrhythmics | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Vasopressors | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Imipramine | Acri AA, Henretig FM | Effects of risperidone in overdose | Am J Emerg Med. 1998 Sep;16(5):498-501 |
Am J Emerg Med | 1998 | Ibuprofen | Ritter A, Eskin B | Ibuprofen overdose presenting with severe agitation and hypothermia | Am J Emerg Med. 1998 Sep;16(5):549-50 |
Am J Emerg Med | 1999 | Fentanyl | Bauman LA, Kish I, Baumann RC, Politis GD | Pediatric sedation with analgesia | Am J Emerg Med. 1999 Jan;17(1):1-3 |
Am J Emerg Med | 1999 | Propofol | Bauman LA, Kish I, Baumann RC, Politis GD | Pediatric sedation with analgesia | Am J Emerg Med. 1999 Jan;17(1):1-3 |
Am J Emerg Med | 1999 | Ethanol | Belson MG, Simon HK | Utility of comprehensive toxicologic screens in children | Am J Emerg Med. 1999 May;17(3):221-4 |
Am J Emerg Med | 1999 | Aspirin | Belson MG, Simon HK | Utility of comprehensive toxicologic screens in children | Am J Emerg Med. 1999 May;17(3):221-4 |
Am J Emerg Med | 1999 | Acetaminophen | Belson MG, Simon HK | Utility of comprehensive toxicologic screens in children | Am J Emerg Med. 1999 May;17(3):221-4 |
Am J Emerg Med | 1999 | Benzodiazepines | Belson MG, Simon HK | Utility of comprehensive toxicologic screens in children | Am J Emerg Med. 1999 May;17(3):221-4 |
Am J Emerg Med | 1999 | Barbiturates | Belson MG, Simon HK | Utility of comprehensive toxicologic screens in children | Am J Emerg Med. 1999 May;17(3):221-4 |
Am J Emerg Med | 1999 | Amphetamines | Belson MG, Simon HK | Utility of comprehensive toxicologic screens in children | Am J Emerg Med. 1999 May;17(3):221-4 |
Am J Emerg Med | 1999 | Cocaine | Belson MG, Simon HK | Utility of comprehensive toxicologic screens in children | Am J Emerg Med. 1999 May;17(3):221-4 |
Am J Emerg Med | 1999 | Phencyclidine | Belson MG, Simon HK | Utility of comprehensive toxicologic screens in children | Am J Emerg Med. 1999 May;17(3):221-4 |
Am J Emerg Med | 1999 | Opiates | Belson MG, Simon HK | Utility of comprehensive toxicologic screens in children | Am J Emerg Med. 1999 May;17(3):221-4 |
Am J Emerg Med | 2000 | Valproic acid | Thabet H, Brahmi N, Amamou M, Ben Salah N, Hedhili A | Hyperlactatemia and hyperammonemia as secondary effects of valproic acid poisoning | Am J Emerg Med. 2000 Jul;18(4):508 |
Am J Emerg Med | 2000 | Albuterol | Yamamoto LG, Okamura D, Nagamine J, Boychuk RB, Halm B, Lee E, Yee LL | Dispensing home nebulizers for acute wheezing from the hospital is cost-effective | Am J Emerg Med. 2000 Mar;18(2):164-7 |
Am J Emerg Med | 2000 | Insulin | Rutledge J, Couch R | Initial fluid management of diabetic ketoacidosis in children | Am J Emerg Med. 2000 Oct;18(6):658-60 |
Am J Emerg Med | 2000 | Heliox | Beckmann KR, Brueggemann WM Jr. | Heliox treatment of severe croup | Am J Emerg Med. 2000 Oct;18(6):735-6 |
Am J Emerg Med | 2000 | Nefazodone | Benson BE, Mathiason M, Dahl B, Smith K, Foley MM, Easom LA, Butler AY | Toxicities and outcomes associated with nefazodone poisoning: an analysis of 1,338 exposures | Am J Emerg Med. 2000 Sep;18(5):587-92 |
Am J Emerg Med | 2001 | Lidocaine | Udezue E. | Lidocaine inhalation for cough suppression | Am J Emerg Med. 2001 May;19(3):206-7 |
Am J Emerg Med | 2001 | Nalmefene | Chumpa A, Kaplan RL, Burns MM, Shannon MW | Nalmefene for elective reversal of procedural sedation in children | Am J Emerg Med. 2001 Nov;19(7):545-8 |
Am J Emerg Med | 2001 | Fentanyl | Chumpa A, Kaplan RL, Burns MM, Shannon MW | Nalmefene for elective reversal of procedural sedation in children | Am J Emerg Med. 2001 Nov;19(7):545-8 |
Am J Emerg Med | 2001 | Midazolam | Chumpa A, Kaplan RL, Burns MM, Shannon MW | Nalmefene for elective reversal of procedural sedation in children | Am J Emerg Med. 2001 Nov;19(7):545-8 |
Am J Emerg Med | 2001 | Hydroxychloroquine | Marquardt K, Albertson TE | Treatment of hydroxychloroquine overdose | Am J Emerg Med. 2001 Sep;19(5):420-4 |
Am J Emerg Med | 2001 | Dopamine | Marquardt K, Albertson TE | Treatment of hydroxychloroquine overdose | Am J Emerg Med. 2001 Sep;19(5):420-4 |
Am J Emerg Med | 2001 | Potassium | Marquardt K, Albertson TE | Treatment of hydroxychloroquine overdose | Am J Emerg Med. 2001 Sep;19(5):420-4 |
Am J Emerg Med | 2001 | Chloroquine | Marquardt K, Albertson TE | Treatment of hydroxychloroquine overdose | Am J Emerg Med. 2001 Sep;19(5):420-4 |
Am J Emerg Med | 2001 | Diazepam | Marquardt K, Albertson TE | Treatment of hydroxychloroquine overdose | Am J Emerg Med. 2001 Sep;19(5):420-4 |
Am J Emerg Med | 2001 | Epinephrine | Marquardt K, Albertson TE | Treatment of hydroxychloroquine overdose | Am J Emerg Med. 2001 Sep;19(5):420-4 |
Am J Emerg Med | 2001 | Activated charcoal | Marquardt K, Albertson TE | Treatment of hydroxychloroquine overdose | Am J Emerg Med. 2001 Sep;19(5):420-4 |
Am J Emerg Med | 2002 | Droperidol | Richman PB, Allegra J, Eskin B, Doran J, Reischel U, Kaiafas C, Nashed AH | A randomized clinical trial to assess the efficacy of intramuscular droperidol for the treatment of acute migraine headache | Am J Emerg Med. 2002 Jan;20(1):39-42 |
Am J Emerg Med | 2002 | Meperidine | Richman PB, Allegra J, Eskin B, Doran J, Reischel U, Kaiafas C, Nashed AH | A randomized clinical trial to assess the efficacy of intramuscular droperidol for the treatment of acute migraine headache | Am J Emerg Med. 2002 Jan;20(1):39-42 |
Am J Emerg Med | 2002 | Cisapride | Richman PB, Allegra J, Eskin B, Doran J, Reischel U, Kaiafas C, Nashed AH | A randomized clinical trial to assess the efficacy of intramuscular droperidol for the treatment of acute migraine headache | Am J Emerg Med. 2002 Jan;20(1):39-42 |
Am J Emerg Med | 2002 | Cimetidine | Richman PB, Allegra J, Eskin B, Doran J, Reischel U, Kaiafas C, Nashed AH | A randomized clinical trial to assess the efficacy of intramuscular droperidol for the treatment of acute migraine headache | Am J Emerg Med. 2002 Jan;20(1):39-42 |
Am J Emerg Med | 2002 | Fentanyl | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 Mar;20(2):83-7 |
Am J Emerg Med | 2002 | Ketamine | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 Mar;20(2):83-7 |
Am J Emerg Med | 2002 | Meperidine | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 Mar;20(2):83-7 |
Am J Emerg Med | 2002 | Methohexital | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 Mar;20(2):83-7 |
Am J Emerg Med | 2002 | Midazolam | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 Mar;20(2):83-7 |
Am J Emerg Med | 2002 | Morphine | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 Mar;20(2):83-7 |
Am J Emerg Med | 2002 | Nitrous oxide | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 Mar;20(2):83-7 |
Am J Emerg Med | 2002 | Propofol | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 Mar;20(2):83-7 |
Am J Emerg Med | 2002 | Ketamine | Hostetler MA, Barnard JA | Removal of esophageal foreign bodies in the pediatric ED: is ketamine an option? | Am J Emerg Med. 2002 Mar;20(2):96-8 |
Am J Emerg Med | 2002 | Midazolam | Hostetler MA, Barnard JA | Removal of esophageal foreign bodies in the pediatric ED: is ketamine an option? | Am J Emerg Med. 2002 Mar;20(2):96-8 |
Am J Emerg Med | 2002 | Fentanyl | Hostetler MA, Barnard JA | Removal of esophageal foreign bodies in the pediatric ED: is ketamine an option? | Am J Emerg Med. 2002 Mar;20(2):96-8 |
Am J Emerg Med | 2002 | Immunoglobulin | Hostetler MA, Barnard JA | Removal of esophageal foreign bodies in the pediatric ED: is ketamine an option? | Am J Emerg Med. 2002 Mar;20(2):96-8 |
Am J Emerg Med | 2002 | Fentanyl | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 May;20(3):139-43 |
Am J Emerg Med | 2002 | Ketamine | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 May;20(3):139-43 |
Am J Emerg Med | 2002 | Meperidine | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 May;20(3):139-43 |
Am J Emerg Med | 2002 | Methohexital | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 May;20(3):139-43 |
Am J Emerg Med | 2002 | Midazolam | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 May;20(3):139-43 |
Am J Emerg Med | 2002 | Morphine | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 May;20(3):139-43 |
Am J Emerg Med | 2002 | Nitrous oxide | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 May;20(3):139-43 |
Am J Emerg Med | 2002 | Propofol | Hostetler MA, Auinger P, Szilagyi PG | Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997 | Am J Emerg Med. 2002 May;20(3):139-43 |
Am J Emerg Med | 2002 | Ketamine | Hostetler MA, Davis CO | Prospective age-based comparison of behavioral reactions occurring after ketamine sedation in the ED | Am J Emerg Med. 2002 Sep;20(5):463-8 |
Am J Emerg Med | 2002 | Saline | Bansal BC, Wiebe RA, Perkins SD, Abramo TJ | Tap water for irrigation of lacerations | Am J Emerg Med. 2002 Sep;20(5):469-72 |
Am J Emerg Med | 2003 | Acetaminophen | Osborne ZP, Bryant SM | Patients discharged with a prescription for acetaminophen-containing narcotic analgesics do not receive appropriate written instructions | Am J Emerg Med. 2003 Jan;21(1):48-50 |
Am J Emerg Med | 2002 | Clonidine | Quail MT, Shannon M | Severe hypothermia caused by clonidine | Am J Emerg Med. 2003 Jan;21(1):86 |
Am J Emerg Med | 2003 | Antidepressants | Spiller HA, Baker SD, Krenzelok EP, Cutino L | Use of dosage as a triage guideline for unintentional cyclic antidepressant (UCA) ingestions in children | Am J Emerg Med. 2003 Sep;21(5):422-4 |
Am J Emerg Med | 2004 | Sedatives | Brown L, Denmark TK, Wittlake WA, Vargas EJ, Watson T, Crabb JW | Procedural sedation use in the ED: management of pediatric ear and nose foreign bodies | Am J Emerg Med. 2004 Jul;22(4):310-4 |
Am J Emerg Med | 2005 | Propofol | Holger JS, Satterlee PA, Haugen S | Nursing use between 2 methods of procedural sedation: Midazolam versus propofol | Am J Emerg Med. 2005 May;23(3):248-52 |
Am J Emerg Med | 2005 | Midazolam | Holger JS, Satterlee PA, Haugen S | Nursing use between 2 methods of procedural sedation: Midazolam versus propofol | Am J Emerg Med. 2005 May;23(3):248-52 |
Am J Emerg Med | 2005 | Etomidate | Hunt GS, Spencer MT, Hays DP | Etomidate and midazolam for procedural sedation: Prospective, randomized trial | Am J Emerg Med. 2005 May;23(3):299-303 |
Am J Emerg Med | 2005 | Midazolam | Hunt GS, Spencer MT, Hays DP | Etomidate and midazolam for procedural sedation: Prospective, randomized trial | Am J Emerg Med. 2005 May;23(3):299-303 |
Am J Emerg Med | 2005 | l–Carnitine | Lovecchio F, Shriki J, Samaddar R | l-carnitine was safely administered in the setting of valproate toxicity | Am J Emerg Med. 2005 May;23(3):321-2 |
Am J Emerg Med | 2005 | Valproate | Lovecchio F, Shriki J, Samaddar R | l-carnitine was safely administered in the setting of valproate toxicity | Am J Emerg Med. 2005 May;23(3):321-2 |
Am J Emerg Med | 2006 | Midazolam | Wolfe TR, Macfarlane TC | Intranasal midazolam therapy for pediatric status epilepticus | Am J Emerg Med. 2006 May;24(3):343-6 |
Am J Emerg Med | 2006 | Diazepam | Wolfe TR, Macfarlane TC | Intranasal midazolam therapy for pediatric status epilepticus | Am J Emerg Med. 2006 May;24(3):343-6 |
Am J Emerg Med | 2006 | Antibiotics | Reid S, Bonadio W | Feasibility of short-term outpatient intravenous antibiotic therapy for the management of infectious conditions in pediatric patients | Am J Emerg Med. 2006 Nov;24(7):839-42 |
Am J Emerg Med | 2006 | Ceftriaxone | Reid S, Bonadio W | Feasibility of short-term outpatient intravenous antibiotic therapy for the management of infectious conditions in pediatric patients | Am J Emerg Med. 2006 Nov;24(7):839-42 |
Am J Emerg Med | 2007 | Beta-agonists | Beers SL, Abramo TJ, Bracken A, Wiebe RA | Bilevel positive airway pressure in the treatment of status asthmaticus in pediatrics | Am J Emerg Med. 2007 Jan;25(1):6-9 |
Am J Emerg Med | 2007 | Sedatives | Cutler KO, Bush AJ, Godambe SA, Gilmore B | The use of a pediatric emergency medicine-staffed sedation service during imaging: a retrospective analysis | Am J Emerg Med. 2007 Jul;25(6):654-61 |
Am J Emerg Med | 2007 | Midazolam | Cutler KO, Bush AJ, Godambe SA, Gilmore B | The use of a pediatric emergency medicine-staffed sedation service during imaging: a retrospective analysis | Am J Emerg Med. 2007 Jul;25(6):654-61 |
Am J Emerg Med | 2007 | Pentobarbital | Cutler KO, Bush AJ, Godambe SA, Gilmore B | The use of a pediatric emergency medicine-staffed sedation service during imaging: a retrospective analysis | Am J Emerg Med. 2007 Jul;25(6):654-61 |
Am J Emerg Med | 2007 | Fentanyl | Cutler KO, Bush AJ, Godambe SA, Gilmore B | The use of a pediatric emergency medicine-staffed sedation service during imaging: a retrospective analysis | Am J Emerg Med. 2007 Jul;25(6):654-61 |
Am J Emerg Med | 2007 | Chloral hydrate | Cutler KO, Bush AJ, Godambe SA, Gilmore B | The use of a pediatric emergency medicine-staffed sedation service during imaging: a retrospective analysis | Am J Emerg Med. 2007 Jul;25(6):654-61 |
Am J Emerg Med | 2007 | Propofol | Cutler KO, Bush AJ, Godambe SA, Gilmore B | The use of a pediatric emergency medicine-staffed sedation service during imaging: a retrospective analysis | Am J Emerg Med. 2007 Jul;25(6):654-61 |
Am J Emerg Med | 2007 | Ketamine | Cutler KO, Bush AJ, Godambe SA, Gilmore B | The use of a pediatric emergency medicine-staffed sedation service during imaging: a retrospective analysis | Am J Emerg Med. 2007 Jul;25(6):654-61 |
Am J Emerg Med | 2007 | Thiopental | Cutler KO, Bush AJ, Godambe SA, Gilmore B | The use of a pediatric emergency medicine-staffed sedation service during imaging: a retrospective analysis | Am J Emerg Med. 2007 Jul;25(6):654-61 |
Am J Emerg Med | 2008 | Morphine | Bounes V, Charpentier S, Houze-Cerfon CH, Bellard C, Ducassé JL | Is there an ideal morphine dose for prehospital treatment of severe acute pain? A randomized, double-blind comparison of 2 doses | Am J Emerg Med. 2008 Feb;26(2):148-54 |
Am J Emerg Med | 2008 | Analgesics | Frei SP, Bond WF, Bazuro RK, Richardson DM, Sierzega GM, Wasser TE | Is early analgesia associated with delayed treatment of appendicitis? | Am J Emerg Med. 2008 Feb;26(2):176-80 |
Am J Emerg Med | 2008 | Fentanyl | Schmerler BL, Cohen DM, Leder MS, Bonsu BK | Procedural sedation for fracture reduction in children with hyperactivity | Am J Emerg Med. 2008 Jul;26(6):661-4 |
Am J Emerg Med | 2008 | Midazolam | Schmerler BL, Cohen DM, Leder MS, Bonsu BK | Procedural sedation for fracture reduction in children with hyperactivity | Am J Emerg Med. 2008 Jul;26(6):661-4 |
Am J Emerg Med | 2008 | Analgesics | Stone MB, Wang R, Price DD | Ultrasound-guided supraclavicular brachial plexus nerve block vs procedural sedation for the treatment of upper extremity emergencies | Am J Emerg Med. 2008 Jul;26(6):706-10 |
Am J Emerg Med | 2008 | Sedatives | Stone MB, Wang R, Price DD | Ultrasound-guided supraclavicular brachial plexus nerve block vs procedural sedation for the treatment of upper extremity emergencies | Am J Emerg Med. 2008 Jul;26(6):706-10 |
Am J Emerg Med | 2009 | ShotBlocker | Drago LA, Singh SB, Douglass-Bright A, Yiadom MY, Baumann BM | Efficacy of ShotBlocker in reducing pediatric pain associated with intramuscular injections | Am J Emerg Med. 2009 Jun;27(5):536-43 |
Am J Emerg Med | 2009 | Antipsychotics | Tan HH, Hoppe J, Heard K | A systematic review of cardiovascular effects after atypical antipsychotic medication overdose | Am J Emerg Med. 2009 Jun;27(5):607-16 |
Am J Emerg Med | 2009 | Aripiprazole | Tan HH, Hoppe J, Heard K | A systematic review of cardiovascular effects after atypical antipsychotic medication overdose | Am J Emerg Med. 2009 Jun;27(5):607-16 |
Am J Emerg Med | 2009 | Olanzapine | Tan HH, Hoppe J, Heard K | A systematic review of cardiovascular effects after atypical antipsychotic medication overdose | Am J Emerg Med. 2009 Jun;27(5):607-16 |